The idea to just pick up and go somewhere on a vacation is a very lovely idea, but for most it hardly ever happens that way. Traveling takes time to prepare for. Time to figure out where you are going. When you are going. How you are going to get there. How you will get around once you are there. Where you will stay. The things you will do while you are there. To simply fly by the seat of your pants and take off in one direction not knowing any of the above information is a wild way to live, although it has been known to happen. For the most part, people think about things a lot longer then a couple of hours before making the choice to go. To begin this planning process you must first know where it is you need to go, or wish to go.
Second, you should figure out what time of the year is best for you to go to this destination, if it happens to be a vacation, if it is a business trip or something more with a hard deadline of a time frame you might not have as much to figure out about when to go. The quickest way to travel is to fly, but for some this is not the best choice. There are also the options of traveling via rail, or the old dusty road. Depending upon what type of trip you are taking you might need to prearrange hotel reservations or set up your accommodations with friends and family. Even if you are traveling for work, you can not possibly work the entire time, why not do a little planning on what there is in the area as far as site seeing, local culture, night life. Everyone can stand for a little enjoyment while out of their realm of normalcy.